A recent study sponsored by the European Chemicals Agency (ECHA) has found that 2-ethylhexanoic acid (2-EHA) has no adverse effects on reproductive function at the highest dose, it was reported 5 April.
Officials at Perstorp, a Sweden-based leading manufacturer of 2-EHA, said the study, which was evaluated and supported by ECHA member state Spain, was carried out on rats.
The study has concluded that no additional classification is required and that there is no need of further risk management measures based on the exposure scenarios assessed in the dossier.
2-EHA (2-ethylhexanoic acid) is widely used in esters for PVB film plasticisers and synthetic lubricants, in production of metal soaps for paint driers, in automotive coolants and PVC stabilisers.
According to Perstorp, 2-EHA will remain classified as reproductive toxicity category 2, meaning consumer use should be restricted and some risk mitigating measures need to be taken into account when used at production facilities.
Due to earlier suspicions about its possible reproductive toxicity, ECHA had 2-EHA listed in the Community Rolling Action Plan (CoRAP) as CMR (reproductive toxicity - fertility) and potential neurodevelopmental toxicity.
This listing has now been removed and 2-EHA is no longer under consideration for additional classification and labeling, Perstorp added.